Description

5-Bromo-n-tert-Butylpyrimidin-2-Amine is a high-purity brominated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized heterocyclic core that enables the development of novel compounds with targeted biological or material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and plant growth regulators that require a functionalized pyrimidine scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical producers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-Bromo-n-tert-Butylpyrimidin-2-Amine
CAS No.	14001-72-0
Molecular Formula	C8H12BrN3
Molecular Weight	230.11 g/mol
Synonyms	5-Bromo-2-amino-N-tert-butylpyrimidine; 2-Amino-5-bromo-N-tert-butylpyrimidine; 5-Bromo-2-(tert-butylamino)pyrimidine; 5-Bromo-N-(tert-butyl)pyrimidin-2-amine; 14001-72-0; tert-Butyl-(5-bromopyrimidin-2-yl)amine; 5-Bromo-2-(tert-butylamino)pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-tert-Butylpyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and production use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.