Description

5-Bromo-2-Methoxypyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its reactive bromine atom and methoxy group, which allow for selective functionalization to create complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of various drug candidates, including kinase inhibitors and antiviral compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating functionalized pyrimidine-based ligands, polymers, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleoside & Nucleotide Chemistry: Used in the modification of nucleosides for medicinal chemistry and biochemical studies.

Basic Information

Product Name	5-Bromo-2-Methoxypyrimidine
CAS No.	14001-66-2
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	2-Methoxy-5-bromopyrimidine; 5-Bromo-2-methoxypyrimidine; 5-Bromo-2-pyrimidinyl methyl ether; 5-Bromo-2-methoxy-pyrimidine; 14001-66-2; 5-Brom-2-methoxypyrimidin; Pyrimidine, 5-bromo-2-methoxy-
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methoxypyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP environments and research requiring the highest material integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.