Description

n-α-Methyl-L-Lysine Hydrochloride is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of the methylated lysine analog. This compound matters as a crucial biochemical building block and research reagent, offering a stable and soluble form for advanced studies in enzymology and molecular biology. It is primarily needed by pharmaceutical R&D teams, biochemical researchers, and fine chemical manufacturers focused on developing enzyme inhibitors, studying post-translational modifications, and synthesizing specialized peptides.

Application

• Biochemical Research: Used as a substrate or inhibitor in studies of lysine-specific enzymes, including methyltransferases and demethylases.
• Pharmaceutical Intermediates: Serves as a key chiral building block in the synthesis of novel therapeutic agents and drug candidates.
• Enzymology Studies: Employed to investigate enzyme kinetics and mechanisms related to protein methylation and epigenetics.
• Peptide Synthesis: Incorporated into custom peptide sequences to study structure-activity relationships and mimic natural post-translational modifications.
• Reference Standard: Utilized as a high-purity analytical standard in HPLC and LC-MS methods for quality control and metabolic studies.
• Cell Culture & Microbiology: Applied in defined media for microbial fermentation or cell culture studies requiring specific amino acid analogs.

Basic Information

Product Name	n-α-Methyl-L-Lysine Hydrochloride
CAS No.	14000-28-3
Molecular Formula	C7H17ClN2O2
Molecular Weight	196.68 g/mol
Synonyms	Nα-Methyl-L-lysine hydrochloride; (S)-2-Amino-6-(methylamino)hexanoic acid hydrochloride; α-Methyl-L-lysine HCl; L-α-Methyllysine hydrochloride; 2-Amino-6-(methylamino)caproic acid hydrochloride; N-Methyl-L-lysine monohydrochloride; N6-Methyl-L-lysine hydrochloride (common misassignment)
EINECS	Contact for details

Quality Control

Our n-α-Methyl-L-Lysine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) and spectroscopic confirmation are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+20.0° to +24.0° (c=1 in H2O)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Chloride Content (Titration)	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.