Description

4-Mercapto-2,6-Dimethylpyrimidine-5-Carbonitrile is a versatile heterocyclic building block characterized by its reactive thiol and nitrile functional groups. This compound matters as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists for constructing pyrimidine-based scaffolds, which are prevalent in active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting kinase inhibition and antiviral activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require a pyrimidine core structure.
• Material Science Research: Serves as a precursor for creating functionalized polymers or ligands for metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the design of probes and inhibitors to study enzymatic processes due to its ability to act as a Michael acceptor or thiol-reactive group.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and photographic chemicals.

Basic Information

Product Name	4-Mercapto-2,6-Dimethylpyrimidine-5-Carbonitrile
CAS No.	13996-06-0
Molecular Formula	C7H7N3S
Molecular Weight	165.22 g/mol
Synonyms	5-Cyano-2,6-dimethyl-4-pyrimidinethiol; 2,6-Dimethyl-4-mercaptopyrimidine-5-carbonitrile; 4-Pyrimidinethiol, 5-cyano-2,6-dimethyl-; 4-Mercapto-2,6-dimethyl-5-pyrimidinecarbonitrile; 5-Cyano-4-mercapto-2,6-dimethylpyrimidine; 2,6-Dimethyl-4-thioxo-3,4-dihydropyrimidine-5-carbonitrile; 4-Thioxo-3,4-dihydro-2,6-dimethylpyrimidine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Mercapto-2,6-Dimethylpyrimidine-5-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.