Description

6,7-Dihydro-1H-Pyrrolo[3,4-D]Pyrimidine-2,4(3H,5H)-Dione Hydrochloride is a high-purity heterocyclic building block essential for advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate in the creation of novel drug candidates, particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of purine and pyrimidine analogue-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing libraries of novel compounds in drug discovery programs.
• Biochemical Reagent: Employed in enzymatic and receptor-binding studies to investigate biological pathways.
• Nucleic Acid Chemistry: Serves as a building block for modified nucleosides and nucleotides in oligonucleotide synthesis.
• Agrochemical Development: Potential intermediate in the research and development of new crop protection agents.
• Academic Research: Used in university and institutional labs for synthetic organic chemistry and heterocyclic chemistry studies.

Basic Information

Product Name	6,7-Dihydro-1H-Pyrrolo[3,4-D]Pyrimidine-2,4(3H,5H)-Dione Hydrochloride
CAS No.	13931-24-3
Molecular Formula	C6H8N3O2 • HCl
Molecular Weight	189.61 g/mol (Free base: 154.15 g/mol)
Synonyms	1H-Pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione, 6,7-dihydro-, hydrochloride; 6,7-Dihydro-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,5H)-dione HCl; 2,4-Dioxo-1,3,4,5,6,7-hexahydropyrrolo[3,4-d]pyrimidine hydrochloride; Tetrahydro-1H-pyrrolo[3,4-d]pyrimidine-2,4-dione hydrochloride; Pyrrolopyrimidinedione hydrochloride; CAS 13931-24-3
EINECS	Contact for details

Quality Control

Our 6,7-Dihydro-1H-Pyrrolo[3,4-D]Pyrimidine-2,4(3H,5H)-Dione Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.