Description

L-Leucic Acid is a high-purity, naturally occurring branched-chain hydroxy acid with significant commercial and research utility. Its unique structure makes it a valuable chiral building block and intermediate in the synthesis of pharmaceuticals, fine chemicals, and advanced materials. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, nutraceutical, and specialty chemical sectors seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for metabolic and neurological drugs.
• Nutraceutical & Dietary Supplements: Used in the research and development of performance-enhancing and muscle recovery supplements.
• Fine Chemical Synthesis: Serves as a versatile building block for producing complex organic molecules, flavors, and fragrances.
• Biochemical Research: Employed in metabolic pathway studies and as a standard in analytical chemistry for method development.
• Cosmetic Actives: Investigated for use in advanced skincare formulations targeting skin renewal and texture improvement.
• Agrochemicals: Potential intermediate in the development of novel, targeted plant growth regulators or pesticides.

Basic Information

Product Name	L-Leucic Acid
CAS No.	13748-90-8
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	(S)-2-Hydroxy-4-methylpentanoic acid; (S)-2-Hydroxyisocaproic acid; L-2-Hydroxy-4-methylvaleric acid; L-α-Hydroxyisocaproic acid; HICA (L-form); Leucic acid; (2S)-2-Hydroxy-4-methylpentanoic acid
EINECS	237-328-1

Quality Control

Our L-Leucic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets exacting standards for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific impurities is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-14.0° to -16.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.