Description

Tetrahydro-1,3-Bis(Hydroxymethyl)-4-Methoxy-5,5-Dimethyl-1H-Pyrimidin-2-One is a versatile heterocyclic compound with a unique pyrimidinone core structure functionalized with hydroxymethyl and methoxy groups. This molecular architecture makes it a valuable building block and intermediate in advanced organic synthesis, particularly for creating complex molecules with specific biological or material properties. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical research and development teams for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) agents and other bioactive heterocycles.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides, herbicides, and plant growth regulators.
• Cross-linking Agent: Its bifunctional hydroxymethyl groups enable its use in polymer chemistry as a cross-linker for resins and specialty coatings.
• Chemical Research (R&D): Serves as a versatile scaffold in medicinal chemistry and material science for structure-activity relationship (SAR) studies.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	Tetrahydro-1,3-Bis(Hydroxymethyl)-4-Methoxy-5,5-Dimethyl-1H-Pyrimidin-2-One
CAS No.	13747-12-1
Molecular Formula	C9H16N2O4
Molecular Weight	216.24 g/mol
Synonyms	1,3-Bis(hydroxymethyl)-4-methoxy-5,5-dimethyl-2-oxohexahydropyrimidine; 4-Methoxy-5,5-dimethyl-1,3-bis(hydroxymethyl)tetrahydropyrimidin-2(1H)-one; DMDMH (in certain contexts); Formaldehyde release agent; Hexahydro-1,3-bis(hydroxymethyl)-4-methoxy-5,5-dimethyl-2(1H)-pyrimidinone; 1,3-Di(hydroxymethyl)-4-methoxy-5,5-dimethyl-2-imidazolidinone (common misnomer); Tetramethylol acetylene diurea derivative
EINECS	Contact for details

Quality Control

Our Tetrahydro-1,3-Bis(Hydroxymethyl)-4-Methoxy-5,5-Dimethyl-1H-Pyrimidin-2-One is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), residual solvents, and related substances are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.