Description

2,2,2-Trifluoro-1-Phenyl-Ethylamine Hcl is a high-purity fluorinated amine hydrochloride salt, a key chiral building block in advanced organic synthesis. Its trifluoromethyl group introduces unique electronic and steric properties, making it invaluable for modulating the biological activity and metabolic stability of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms enhance lipophilicity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology & Proteomics: Acts as a building block for activity-based probes and molecular tags in biochemical research.

Basic Information

Product Name	2,2,2-Trifluoro-1-Phenyl-Ethylamine Hcl
CAS No.	13652-09-0
Molecular Formula	C8H9ClF3N
Molecular Weight	211.61 g/mol
Synonyms	(R/S)-1-Phenyl-2,2,2-trifluoroethylamine hydrochloride; α-(Trifluoromethyl)benzylamine hydrochloride; 1-Phenyl-2,2,2-trifluoroethanamine hydrochloride; 2,2,2-Trifluoro-1-phenylethanamine hydrochloride; (RS)-1-Phenyl-2,2,2-trifluoroethylamine HCl; TFPEA HCl; Benzylamine, α-(trifluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2,2,2-Trifluoro-1-Phenyl-Ethylamine Hcl is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive testing includes identity confirmation, purity assay, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Contact for details (Racemic or Enantiopure grades available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.