Description

H-Leu-Val-Oh is a high-purity dipeptide building block, specifically the C-terminal carboxylic acid derivative of the Leu-Val sequence. This compound is a critical intermediate for the synthesis of more complex peptides and peptidomimetics, offering precise control over molecular structure. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors engaged in drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block for the solid-phase and solution-phase synthesis of therapeutic peptides targeting metabolic disorders, cardiovascular diseases, and oncology.
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or inhibitor model to investigate enzyme specificity and peptide-protein interactions.
• Peptidomimetic Development: Serves as a core scaffold for designing and synthesizing novel peptidomimetics with enhanced stability and bioavailability.
• Cosmetic Peptide Synthesis: Incorporated into the production of bioactive peptides for advanced skincare formulations aimed at anti-aging and skin repair.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation in peptide analysis.

Basic Information

Product Name	H-Leu-Val-Oh
CAS No.	13588-95-9
Molecular Formula	C11H22N2O3
Molecular Weight	230.31 g/mol
Synonyms	L-Leucyl-L-valine; H-Leu-Val-OH; Leu-Val; L-Leu-L-Val; N-(2-Amino-4-methylpentanoyl)-L-valine; (2S)-2-[[(2S)-2-Amino-4-methylpentanoyl]amino]-3-methylbutanoic acid; L-Valine, N-L-leucyl-; Peptide Building Block 13588-95-9
EINECS	Contact for details

Quality Control

Our H-Leu-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccant or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.