Description

2, 4-Dichloro-5-Iodopyrimidine is a versatile halogenated pyrimidine building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by R&D chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs), nucleoside analogs, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of antiviral, anticancer, and other biologically active nucleoside analogs and heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for cross-coupling reactions (e.g., Suzuki, Sonogashira) to introduce diverse functional groups at specific positions on the pyrimidine ring.
• Material Science: Potential building block for the creation of organic electronic materials, ligands for catalysts, and specialty polymers.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of client-specific target molecules under cGMP or non-GMP conditions.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2, 4-Dichloro-5-Iodopyrimidine
CAS No.	13544-44-0
Molecular Formula	C4HCl2IN2
Molecular Weight	274.87 g/mol
Synonyms	5-Iodo-2,4-dichloropyrimidine; 2,4-Dichloro-5-iodopyrimidine; 5-Iodo-2,4-dichloro-pyrimidine; Pyrimidine, 2,4-dichloro-5-iodo-; 13544-44-0; 2,4-Dichloro-5-iodo-pyrimidine; 2,4-Dichloro-5-iodo pyrimidine
EINECS	Contact for details

Quality Control

Our 2, 4-Dichloro-5-Iodopyrimidine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.