Description

6-Hydroxy-5,6-Dihydrothymine is a high-purity pyrimidine derivative, a key intermediate in the synthesis of nucleosides and modified nucleic acids. This compound matters for its role in advanced pharmaceutical research and the development of novel therapeutic agents, offering a critical building block for precise molecular construction. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on oncology, antiviral, and genetic research applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel nucleoside analogs and antimetabolites for cancer and antiviral therapies.
• Biochemical Research: Used as a standard or reagent in studies of DNA damage, repair mechanisms, and oxidative stress on nucleic acids.
• Fine Chemical Synthesis: Serves as a specialized building block for creating modified oligonucleotides and labeled probes for diagnostic applications.
• Academic & R&D Laboratories: Employed in mechanistic studies and the development of new synthetic methodologies in organic and medicinal chemistry.

Basic Information

Product Name	6-Hydroxy-5,6-Dihydrothymine
CAS No.	13514-92-6
Molecular Formula	C5H8N2O3
Molecular Weight	144.13 g/mol
Synonyms	5,6-Dihydro-6-hydroxythymine; 6-Hydroxydihydrothymine; 5,6-Dihydrothymine-6-ol; Thymine glycol (referring to a diastereomeric mixture); 5-Methyl-6-hydroxy-5,6-dihydrouracil; 5-Methyl-5,6-dihydrouracil-6-ol; 6-Hydroxy-5-methyl-5,6-dihydropyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-5,6-Dihydrothymine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While produced to meet general reagent and fine chemical standards, specifications can be aligned with customer-specific requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.