Description

2-Pyrimidineacetonitrile, 1,6-Dihydro-4-Methyl-6-Oxo- (8Ci) is a high-purity heterocyclic nitrile building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce functionalized pyrimidine cores into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators containing pyrimidine motifs.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for creating specialty chemicals, dyes, and functional materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and for exploring new chemical entities in discovery programs.

Basic Information

Product Name	2-Pyrimidineacetonitrile, 1,6-Dihydro-4-Methyl-6-Oxo- (8Ci)
CAS No.	13514-85-7
Molecular Formula	C7H7N3O
Molecular Weight	149.15 g/mol
Synonyms	1,6-Dihydro-4-methyl-6-oxo-2-pyrimidineacetonitrile; 4-Methyl-6-oxo-1,6-dihydro-2-pyrimidineacetonitrile; 2-(Cyanomethyl)-4-methyl-6-hydroxypyrimidine; 4-Methyl-6-hydroxy-2-pyrimidineacetonitrile; 6-Hydroxy-4-methyl-2-pyrimidineacetonitrile; (4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 2-Pyrimidineacetonitrile, 1,6-Dihydro-4-Methyl-6-Oxo- (8Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.