Description

All-trans-Retinoic Acid Sodium Salt is the water-soluble sodium salt form of all-trans-retinoic acid, a potent and biologically active metabolite of Vitamin A. This compound is critical for research and development in life sciences due to its role as a high-purity reference standard and active pharmaceutical ingredient. It is primarily required by pharmaceutical manufacturers, biotechnology companies, and advanced research institutions for applications in oncology, dermatology, and cell differentiation studies.

Application

• Pharmaceutical Active Ingredient (API): Used in the formulation of topical and systemic medications targeting dermatological conditions and certain cancers.
• Biochemical Research: Serves as a crucial ligand and differentiation agent in cell culture studies, particularly in stem cell and cancer research.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and other chromatographic methods.
• Cosmeceutical R&D: Investigated for use in advanced anti-aging and skin-renewal formulations due to its cell-regulating properties.

Basic Information

Product Name	All-trans-Retinoic Acid Sodium Salt
CAS No.	13497-05-7
Molecular Formula	C20H27NaO2
Molecular Weight	322.42 g/mol
Synonyms	Tretinoin Sodium Salt; Retinoic Acid Sodium Salt; Vitamin A Acid Sodium Salt; all-trans-Retinoate Sodium; (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic Acid Sodium Salt; Sodium Tretinoate; ATRA Sodium Salt
EINECS	Contact for details

Quality Control

Our All-trans-Retinoic Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.