Description

H-Asp(Phe-Oh)-Oh is a protected dipeptide derivative, specifically aspartyl-phenylalanine, where the side chain carboxyl group of aspartic acid is protected. This compound is a crucial pharmaceutical intermediate and a key building block in advanced peptide synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic peptides and APIs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Peptide Synthesis Building Block: Used in solid-phase and solution-phase peptide synthesis (SPPS) for constructing specific peptide sequences.
• Research & Development: Employed in biochemical and medicinal chemistry research for studying peptide structure-activity relationships.
• Aspartame Analog Synthesis: Serves as a starting material or intermediate in the research and production of aspartame and related high-intensity sweeteners.
• Enzyme Substrate Studies: Can be used as a substrate or inhibitor in enzymatic studies related to proteases and peptidases.

Basic Information

Product Name	H-Asp(Phe-Oh)-Oh
CAS No.	13433-10-8
Molecular Formula	C13H16N2O5
Molecular Weight	280.28 g/mol
Synonyms	Asp-Phe-OH; L-Aspartyl-L-phenylalanine; Aspartylphenylalanine; H-Asp-Phe-OH; N-(Benzyloxycarbonyl)-L-aspartyl-L-phenylalanine; Z-Asp-Phe-OH; Aspartame precursor; Protected Asp-Phe dipeptide
EINECS	Contact for details

Quality Control

Our H-Asp(Phe-Oh)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.