Description

H-Cys(Me)-Oh.Hcl is a protected derivative of the amino acid cysteine, specifically S-methyl-L-cysteine hydrochloride. This compound is a crucial building block in peptide synthesis, offering a stable thioether-protected side chain that prevents unwanted disulfide bond formation during complex peptide assembly. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutic peptides, peptidomimetics, and biochemical research where precise cysteine incorporation is required.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected amino acid for the controlled introduction of cysteine residues into peptide chains.
• Pharmaceutical Intermediates: Serves as a critical raw material in the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in the study of protein structure, function, and folding mechanisms.
• Peptidomimetic Drug Design: A building block for creating stable, drug-like molecules that mimic natural peptides.
• Ligand Synthesis: For the preparation of chelating agents or ligands in metal-catalyzed reactions or diagnostic imaging.

Basic Information

Product Name	H-Cys(Me)-Oh.Hcl
CAS No.	13331-74-3
Molecular Formula	C4H10ClNO2S
Molecular Weight	171.64 g/mol
Synonyms	S-Methyl-L-cysteine hydrochloride; (R)-2-Amino-3-(methylthio)propanoic acid hydrochloride; L-Cysteine, S-methyl-, hydrochloride; H-Cys(Me)-OH·HCl; Fmoc-Cys(Me)-OH precursor; Cysteine methyl ether hydrochloride
EINECS	Contact for details

Quality Control

Our H-Cys(Me)-Oh.Hcl is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for peptide synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity (by HPLC), chiral purity, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.