Description

Gentamicin A CAS NO 13291-74-2 is a major component of the gentamicin antibiotic complex, a clinically significant aminoglycoside. It serves as a critical reference standard and intermediate for pharmaceutical research and development, ensuring the quality and efficacy of related antibiotic formulations. This high-purity compound is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and analytical chemistry sectors who require reliable materials for quality control, method validation, and synthesis.

Application

• Pharmaceutical Reference Standard: Used as a primary standard in HPLC and other analytical methods for the quantification and purity assessment of gentamicin sulfate and related antibiotic preparations.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis and purification of the gentamicin antibiotic complex for medicinal use.
• Microbiological Research: Employed in studies investigating the structure-activity relationships, mechanism of action, and resistance profiles of aminoglycoside antibiotics.
• Quality Control & Assurance: Critical for in-house testing by API manufacturers and finished dosage form producers to comply with pharmacopeial standards (USP, EP).
• Analytical Method Development: Utilized by contract research organizations (CROs) and testing laboratories to develop and validate new assay protocols.

Basic Information

Product Name	Gentamicin A
CAS No.	13291-74-2
Molecular Formula	C18H36N4O10
Molecular Weight	468.50 g/mol
Synonyms	Gentamicin A1; Gentamicin A Component; O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-D-streptamine; Antibiotic G 418 Component A; Sch 14342 Component A; Garamycin A Component
EINECS	Contact for details

Quality Control

Our Gentamicin A is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for use as a reference material. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to support compliance with USP, EP, or other relevant pharmacopeial monographs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.