Description

Z-Ala-Tyr-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z)-protected form of alanyl-tyrosine. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of longer, more complex peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled elongation of peptide sequences in automated synthesizers.
• Pharmaceutical Research: Used in the R&D of new peptide-based drugs, including hormone analogs, enzyme inhibitors, and targeted therapeutics.
• Bioconjugation: Acts as a precursor for creating peptide-protein or peptide-small molecule conjugates for drug delivery systems.
• Biochemical Tool Development: Employed in the synthesis of substrates, inhibitors, or standards for enzymatic assays and proteomics research.
• Custom Peptide Services: A fundamental raw material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide production.

Basic Information

Product Name	Z-Ala-Tyr-Oh
CAS No.	13122-97-9
Molecular Formula	C20H22N2O6
Molecular Weight	386.40 g/mol
Synonyms	N-Cbz-L-alanyl-L-tyrosine; Z-L-Ala-L-Tyr-OH; N-[(Benzyloxy)carbonyl]-L-alanyl-L-tyrosine; Nα-Carbobenzoxy-L-alanyl-L-tyrosine; Cbz-Ala-Tyr-OH; CBZ-L-Alanyl-L-Tyrosine; Benzyloxycarbonylalanyltyrosine; N-Carbobenzoxy-L-alanyl-L-tyrosine
EINECS	Contact for details

Quality Control

Our Z-Ala-Tyr-Oh is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric integrity, and spectroscopic methods for structural confirmation. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and other critical impurities, ensuring the material meets the stringent requirements for advanced research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term stability, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-15.0° to -20.0° (c=1 in DMF)
Chiral Purity	≥ 99.0% (L-L isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.