Description

Boc-Phe-Phe-Oh CAS NO 13122-90-2 is a protected dipeptide derivative, specifically N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-phenylalanine, widely used as a crucial building block in solid-phase peptide synthesis (SPPS). Its primary value lies in providing a controlled method for elongating peptide chains while protecting the amine functionality of the phenylalanine residue. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing novel therapeutic peptides and conducting biochemical research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of longer, complex therapeutic peptide sequences.
• Biochemical Research: Used in studies of peptide structure-activity relationships (SAR) and enzyme-substrate interactions.
• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent in Fmoc/t-Bu and Boc/Bzl strategies for the controlled, sequential addition of amino acids.
• Antibiotic & Hormone Analog Development: Serves as a precursor in the research and production of peptide-based antibiotics and hormone analogs.
• Neuroscience Research: Potential use in synthesizing neuropeptides or their fragments for neurological studies.
• Custom Peptide Service Providers: A standard raw material for CROs and CDMOs offering bespoke peptide synthesis services.

Basic Information

Product Name	Boc-Phe-Phe-Oh
CAS No.	13122-90-2
Molecular Formula	C24H30N2O5
Molecular Weight	426.51 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-phenylalanyl-L-phenylalanine; Boc-L-Phenylalanyl-L-phenylalanine; Boc-Phe-Phe-OH; BOC-PHE-PHE; (2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid; N-Boc-L-phenylalanyl-L-phenylalanine; Boc-Phenylalanine-Phenylalanine; Nα-Boc-L-Phe-L-Phe-OH
EINECS	Contact for details

Quality Control

Our Boc-Phe-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance in GMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	-15.0° to -20.0° (c=1 in DMF)
Chiral Purity (HPLC)	≥99.0% (L-L isomer)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.