Description

5-Hydroxypipecolic Acid is a non-proteinogenic amino acid derivative belonging to the pipecolic acid family. This compound serves as a versatile chiral building block and intermediate in organic synthesis and pharmaceutical research. It is particularly valuable for the development of active pharmaceutical ingredients (APIs), peptide mimetics, and other biologically active compounds. The product is supplied under the CAS registry number 13096-31-6.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, including protease inhibitors and other therapeutic agents.
• Peptide Chemistry: Used in the design and synthesis of modified peptides and peptidomimetics to enhance stability, bioavailability, or biological activity.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and enzymatic research related to amino acid metabolism.
• Agrochemical Development: Potential intermediate for creating novel, high-value crop protection agents and plant growth regulators.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical reactions to construct complex molecular architectures.

Basic Information

Product Name	5-Hydroxypipecolic Acid
CAS No.	13096-31-6
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	5-Hydroxypipecolic acid; (2S,5S)-5-Hydroxypipecolic acid; 5-Hydroxy-L-pipecolic acid; 5-Hydroxy-DL-pipecolic acid; 5-Hydroxy-2-piperidinecarboxylic acid; 5-Hydroxy-2-piperidinecarboxylic acid; 5-Hydroxypipecolate; 5-Hydroxyhomoproline
EINECS	Contact for details

Quality Control

Our 5-Hydroxypipecolic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing specific batch results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiomerically pure grades)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.