Description

L-Cysteine-Glutathione Disulfide is a biologically significant mixed disulfide compound formed between the amino acid cysteine and the tripeptide antioxidant glutathione. This molecule plays a crucial role in cellular redox signaling and thiol-disulfide exchange processes, serving as a key intermediate in metabolic pathways. It is of primary interest to researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced biochemical synthesis sectors for developing redox-modulating agents and studying oxidative stress mechanisms.

Application

• Pharmaceutical Intermediate: Used in the research and development of drugs targeting oxidative stress-related conditions, such as neurodegenerative diseases, metabolic disorders, and aging.
• Biochemical Research: Serves as a critical standard and reagent in studies of glutathione metabolism, redox biology, and thiol-disulfide homeostasis.
• Nutraceutical Formulation: Investigated for inclusion in advanced antioxidant supplements designed to support cellular defense systems.
• Enzyme Activity Studies: Employed as a substrate or modulator in enzymatic assays related to glutathione peroxidase, glutathione reductase, and other redox enzymes.
• Cell Culture & Media Supplement: Used in specialized cell culture applications to modulate the redox environment and study cell signaling under controlled oxidative conditions.

Basic Information

Product Name	L-Cysteine-Glutathione Disulfide
CAS No.	13081-14-6
Molecular Formula	C13H22N4O8S2
Molecular Weight	426.47 g/mol
Synonyms	L-Cysteine, S-(L-γ-glutamyl-L-cysteinylglycyl)-; Cys-Gly disulfide; Cysteine-glutathione mixed disulfide; γ-Glutamylcysteinylglycine-cysteine disulfide; Glutathione-Cysteine Disulfide; (2R)-2-Amino-3-[[(2R)-1-[[(2R)-1-[(2R)-2-amino-2-carboxyethyl]disulfanyl]-1-oxo-3-[(carboxymethyl)amino]-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-oxopropanoic acid; CGSSG; Cys-SSG
EINECS	Contact for details

Quality Control

Our L-Cysteine-Glutathione Disulfide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We can support development projects requiring compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere such as argon or nitrogen. Keep the container tightly sealed to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.