Description

L-Ethionine is a sulfur-containing amino acid analog, specifically the L-isomer of ethionine. This compound is a critical research tool and biochemical building block, valued for its ability to interfere with methionine metabolism. It is primarily utilized in biochemical research, pharmaceutical development, and as a reference standard. Industries requiring high-purity amino acid derivatives for metabolic studies, enzyme inhibition research, or analytical applications will find this product essential.

Application

• Biochemical Research: Used as a methionine antagonist to study amino acid metabolism, protein synthesis, and methylation processes in cellular and molecular biology.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and quality control of novel therapeutic agents and metabolic inhibitors.
• Nutritional Science: Employed in studies investigating the effects of amino acid imbalance and sulfur metabolism in experimental models.
• Enzyme Studies: Acts as a substrate analog for methionine adenosyltransferase and other enzymes involved in the methionine cycle for kinetic and inhibition assays.
• Analytical Reference Standard: Used in HPLC, LC-MS, and other chromatographic methods for the identification and quantification of amino acids in complex matrices.
• Microbiology: Applied in microbial growth media formulations to study methionine auxotrophy and related genetic pathways.

Basic Information

Product Name	L-Ethionine
CAS No.	13073-35-3
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	(S)-2-Amino-4-(ethylthio)butyric acid; L-2-Amino-4-(ethylthio)butyric acid; Ethionine, L-; (S)-Ethionine; L-α-Amino-γ-ethylmercaptobutyric acid; NSC 75184; Ethionine (L-form); H-Ethionine-OH
EINECS	235-978-9

Quality Control

Our L-Ethionine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (by HPLC), optical rotation, residue on ignition, and heavy metals. The product is suitable for research and development applications requiring high-purity standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	-24.0° to -28.0° (c=1 in 1N HCl)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.