Description

D-Buthionine is the D-enantiomer of the non-proteinogenic amino acid buthionine, a key compound in the study of glutathione metabolism and cellular redox processes. Its primary value lies in its role as a selective biochemical tool and reference standard, enabling precise research into enzyme specificity and metabolic pathways. This high-purity material is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced life science sectors who require enantiomerically pure compounds for method development, analytical testing, and biochemical synthesis.

Application

• Biochemical Research: Used as a selective inhibitor and probe to study the stereospecificity of enzymes like γ-glutamylcysteine synthetase in glutathione biosynthesis pathways.
• Pharmaceutical Reference Standard: Serves as a critical certified reference material (CRM) for the quality control and analytical method validation of related pharmaceutical compounds and metabolites.
• Metabolic Pathway Analysis: Employed in cell culture and in vitro studies to investigate the role of glutathione in oxidative stress, detoxification, and cellular defense mechanisms.
• Chiral Synthesis Intermediate: Acts as a building block or precursor in the asymmetric synthesis of more complex, biologically active molecules for drug discovery programs.
• Diagnostic Reagent Development: Utilized in the formulation and calibration of diagnostic kits and assays designed to measure glutathione-related enzyme activities.

Basic Information

Product Name	D-Buthionine
CAS No.	13073-22-8
Molecular Formula	C8H17NO4S
Molecular Weight	223.29 g/mol
Synonyms	D-Butionine; (R)-2-Amino-4-(carboxy-methylthio)butyric acid; D-2-Amino-4-(2-carboxyethylthio)butyric acid; (R)-Buthionine; D-Butionine; D-Buthionine sulfoximine precursor; (R)-Homo cysteine, S-(2-carboxyethyl)-; D-Form of Buthionine
EINECS	Contact for details

Quality Control

Our D-Buthionine CAS NO 13073-22-8 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.