Description

Glycohyodeoxycholic Acid is a secondary bile acid conjugate, specifically the glycine conjugate of hyodeoxycholic acid, known for its role in cholesterol metabolism and its potential as a key biochemical intermediate. This high-purity compound is essential for research and development in advanced pharmaceutical synthesis and metabolic studies. It is primarily utilized by biotechnology firms, pharmaceutical R&D laboratories, and academic institutions focused on hepatology, gastroenterology, and novel therapeutic agent development.

Application

• Pharmaceutical Intermediate: Critical starting material or building block in the synthesis of novel therapeutic agents, particularly those targeting metabolic and liver diseases.
• Biochemical Research: Used as a reference standard and reagent in studies of bile acid metabolism, cholesterol homeostasis, and liver function.
• Cell Culture & In Vitro Studies: Employed in laboratory settings to investigate the effects of bile acids on cell signaling, apoptosis, and membrane dynamics.
• Analytical Standard: Serves as a high-purity calibration standard in HPLC, LC-MS, and other analytical methods for quantifying bile acid profiles in biological samples.
• Metabolic Pathway Investigation: A tool for exploring the enterohepatic circulation and the role of conjugated bile acids in digestion and absorption.

Basic Information

Product Name	Glycohyodeoxycholic Acid
CAS No.	13042-33-6
Molecular Formula	C₂₆H₄₃NO₅
Molecular Weight	449.63 g/mol
Synonyms	Glycohyodeoxycholic Acid; N-[(3α,6α)-3,6-Dihydroxy-5β-cholan-24-oyl]glycine; Hyodeoxycholic Acid Glycine Conjugate; Glycine Hyodeoxycholate; 3α,6α-Dihydroxy-5β-cholan-24-oic Acid N-(Carboxymethyl)amide; GDCA; GHDCA
EINECS	Contact for details

Quality Control

Our Glycohyodeoxycholic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and NMR, to ensure it meets stringent specifications for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.