Description

2-Amino-6-[(1S,2R)-1,2-Dihydroxypropyl]-4(1H)-Pteridinone is a high-purity, stereochemically defined pteridinone derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, valued for its unique chiral dihydroxypropyl side chain. It is primarily utilized by research institutions, pharmaceutical R&D labs, and fine chemical manufacturers engaged in the development of novel therapeutics and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of folate analogs and other bioactive pteridine-based compounds.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and metabolic pathway investigations.
• Organic Synthesis Building Block: Employed in the construction of complex heterocyclic systems for medicinal chemistry and material science.
• Reference Material: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Preclinical Development: Utilized in the early-stage development of potential drug candidates targeting specific enzymes or receptors.

Basic Information

Product Name	2-Amino-6-[(1S,2R)-1,2-Dihydroxypropyl]-4(1H)-Pteridinone
CAS No.	13039-62-8
Molecular Formula	C9H11N5O3
Molecular Weight	237.22 g/mol
Synonyms	(1S,2R)-2-Amino-6-(1,2-dihydroxypropyl)-1,4-dihydropteridin-4-one; 6-[(1S,2R)-1,2-Dihydroxypropyl]-2-amino-4(1H)-pteridinone; L-Biopterin intermediate; (6R)-L-erythro-Biopterin analog; 2-Amino-6-(L-erythro-1,2-dihydroxypropyl)-4(3H)-pteridinone; 2-Amino-6-[(1S,2R)-1,2-dihydroxypropyl]pteridin-4(1H)-one
EINECS	Contact for details

Quality Control

Our production of 2-Amino-6-[(1S,2R)-1,2-Dihydroxypropyl]-4(1H)-Pteridinone adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized and accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We support development and cGMP manufacturing needs with scalable, well-documented processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (1S,2R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.