Description

Butirosin is an aminoglycoside antibiotic complex derived from *Bacillus circulans*, known for its activity against Gram-negative bacteria. This compound is of significant interest in pharmaceutical research and development, particularly for studying antibiotic mechanisms and resistance. It serves as a critical intermediate and reference standard for laboratories and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for quality control and analytical method development in antibiotic production.
• Antibiotic Research: A key tool in microbiological and biochemical research to study aminoglycoside action, bacterial resistance mechanisms, and structure-activity relationships.
• Intermediate Synthesis: Serves as a starting material or intermediate in the synthesis of novel antibiotic derivatives and analogs.
• Microbiological Assays: Employed in agar diffusion and other microbiological assays to determine antibiotic potency or screen for antimicrobial activity.
• Veterinary Medicine Research: Investigated for potential applications in animal health for treating bacterial infections.

Basic Information

Product Name	Butirosin
CAS No.	12772-35-9
Molecular Formula	C₂₁H₄₁N₅O₁₂
Molecular Weight	555.58 g/mol
Synonyms	Butirosin Sulfate; Antibiotic Bu 1709; Bu-1709 A1; Bu-1709 A2; Butirosin A; Butirosin B; 1-N-[(S)-4-Amino-2-hydroxybutyryl]-ribostamycin; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine, 1-N-[(S)-4-Amino-2-hydroxybutanoyl] derivative
EINECS	Contact for details

Quality Control

Our Butirosin is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and potency, meeting the requirements for research and reference standard use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and microbiological purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
pH (Solution)	5.0 - 7.5
Residue on Ignition	≤ 1.0%
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.