Description

Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-Nh2 3Acoh 5H2O is a synthetic peptide acetate salt hydrate, a derivative of the naturally occurring peptide substance P. This compound is of significant interest for its role as a research-grade biochemical tool and a key intermediate in advanced pharmaceutical development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in neurobiology, inflammation studies, and peptide-based drug discovery. The product is supplied with a CAS Registry Number of 11035-08-8.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of neurokinin receptors (NK1, NK2, NK3) and related signaling pathways.
• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of novel therapeutic peptides targeting pain, inflammation, and central nervous system disorders.
• In Vitro Diagnostics: Employed in the development of competitive immunoassays and enzyme-linked immunosorbent assays (ELISAs) for substance P and its metabolites.
• Cell Culture & Physiology Studies: Applied in experimental models to investigate smooth muscle contraction, vasodilation, and neurogenic inflammation.
• Neuroscience Research: A vital tool for exploring the role of tachykinins in neurotransmission, nociception, and emotional behavior.
• Preclinical Development: Used in pharmacokinetic and pharmacodynamic studies during the early stages of drug candidate evaluation.

Basic Information

Product Name	Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-Nh2 3Acoh 5H2O
CAS No.	11035-08-8
Molecular Formula	C64H101N19O16S • 3C2H4O2 • 5H2O
Molecular Weight	Contact for details
Synonyms	Substance P (5-11) Fragment Acetate Hydrate; Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-NH2 Acetate Hydrate; SP (5-11); [pGlu5, MePhe8, Sar9]-Substance P (5-11); Neurokinin Peptide Fragment; H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-NH2 acetate salt hydrate; Tachykinin Fragment Acetate
EINECS	Contact for details

Quality Control

Our Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-Nh2 3Acoh 5H2O is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, mass spectrometry (MS) for structural verification, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with research-grade standards. Custom synthesis and purification to meet specific purity requirements (e.g., >95%, >98%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider desiccant and under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	Contact for details
Acetate Content (HPLC/Titration)	Contact for details
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.