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(3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D\-Glucopyranosyl-β-D\-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide CAS NO 11006-14-7


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CAS No.:11006-14-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D-Glucopyranosyl-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide is a high-purity cardiac glycoside derivative, a compound class known for its potent biological activity. This product is critical for pharmaceutical research and development, particularly in the study of cardiovascular therapeutics and drug discovery. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and the investigation of cardiac mechanisms.

Application

  • Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in drug manufacturing.
  • Active Pharmaceutical Ingredient (API) Intermediate: Used as a key building block in the multi-step synthesis of complex cardiac glycoside-based drugs.
  • Biochemical Research: Employed in in vitro and in vivo studies to investigate sodium-potassium ATPase inhibition and cardiac contractility.
  • Drug Discovery & Development: A vital scaffold for medicinal chemists exploring new derivatives with optimized therapeutic profiles and reduced toxicity.
  • Analytical Testing: Used to calibrate instruments (HPLC, LC-MS) and develop assays for the quantification of related compounds in biological matrices.

Basic Information

Product Name (3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D-Glucopyranosyl-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide
CAS No. 11006-14-7
Molecular Formula C35H54O14
Molecular Weight 698.80 g/mol
Synonyms Desglucouzarin; Uzarigenin 3-O-β-D-digitaloside; 3-[(O-6-Deoxy-β-D-glucopyranosyl-(1->4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-β-D-digitoxopyranosyl)oxy]-5,14,19-trihydroxycard-20(22)-enolide; Strophanthidin 3-O-β-D-digitaloside; 3beta-[(O-β-D-Glucopyranosyl-(1->4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-β-D-digitoxopyranosyl)oxy]-5beta,14beta,19-trihydroxycard-20(22)-enolide
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Quality Control

Our (3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D-Glucopyranosyl-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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