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(3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D\-Glucopyranosyl-β-D\-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide CAS NO 11006-14-7
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CAS No.:11006-14-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D-Glucopyranosyl-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide is a high-purity cardiac glycoside derivative, a compound class known for its potent biological activity. This product is critical for pharmaceutical research and development, particularly in the study of cardiovascular therapeutics and drug discovery. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and the investigation of cardiac mechanisms.
Application
- Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in drug manufacturing.
- Active Pharmaceutical Ingredient (API) Intermediate: Used as a key building block in the multi-step synthesis of complex cardiac glycoside-based drugs.
- Biochemical Research: Employed in in vitro and in vivo studies to investigate sodium-potassium ATPase inhibition and cardiac contractility.
- Drug Discovery & Development: A vital scaffold for medicinal chemists exploring new derivatives with optimized therapeutic profiles and reduced toxicity.
- Analytical Testing: Used to calibrate instruments (HPLC, LC-MS) and develop assays for the quantification of related compounds in biological matrices.
Basic Information
| Product Name | (3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D-Glucopyranosyl-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide |
| CAS No. | 11006-14-7 |
| Molecular Formula | C35H54O14 |
| Molecular Weight | 698.80 g/mol |
| Synonyms | Desglucouzarin; Uzarigenin 3-O-β-D-digitaloside; 3-[(O-6-Deoxy-β-D-glucopyranosyl-(1->4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-β-D-digitoxopyranosyl)oxy]-5,14,19-trihydroxycard-20(22)-enolide; Strophanthidin 3-O-β-D-digitaloside; 3beta-[(O-β-D-Glucopyranosyl-(1->4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1->4)-β-D-digitoxopyranosyl)oxy]-5beta,14beta,19-trihydroxycard-20(22)-enolide |
| EINECS | Contact for details |
Quality Control
Our (3Beta,5Beta)-3-[(2,6-Dideoxy-4-o-β-D-Glucopyranosyl-β-D-Ribo-Hexopyranosyl)Oxy]-5,14,19-Trihydroxycard-20(22)-Enolide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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