Description

H-Ala-Ala-Ala-Ala-Ala-Ala-Oh is a synthetic hexapeptide composed of six consecutive alanine residues with a free C-terminal carboxylic acid. This compound serves as a critical model substrate and building block in biochemical and pharmaceutical research, particularly for studying enzyme kinetics, peptide stability, and structure-activity relationships. It is essential for researchers and manufacturers in the fields of proteomics, peptide synthesis, and the development of novel therapeutic agents and diagnostic tools.

Application

• Biochemical Research: Used as a standard substrate for studying the activity and specificity of proteolytic enzymes like proteases and peptidases.
• Pharmaceutical Development: Serves as a key intermediate or model compound in the synthesis and design of more complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Proteomics & Diagnostics: Employed in calibration, method development, and as a reference standard in mass spectrometry and chromatographic analyses.
• Academic Studies: Fundamental tool for investigating peptide folding, aggregation behavior, and physicochemical properties in academic laboratories.
• Enzyme Inhibitor Screening: Acts as a substrate in high-throughput assays to identify and characterize novel enzyme inhibitors.
• Cosmetic Peptide Research: Investigated for potential applications in cosmetic formulations targeting skin conditioning and anti-aging.

Basic Information

Product Name	H-Ala-Ala-Ala-Ala-Ala-Ala-Oh
CAS No.	10576-91-7
Molecular Formula	C18H31N6O7
Molecular Weight	443.48 g/mol
Synonyms	Hexaalanine; H-Ala6-OH; Alanine hexapeptide; Poly-L-alanine (n=6); L-Alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanine; AAAAAA; (Ala)6; NSC 334368
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-Ala-Ala-Ala-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.