Description

4'-Fluoro-Biphenyl-3-Ylamine is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both an aromatic amine and a fluorine-substituted biphenyl system, which enables precise molecular design for performance materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorinated aromatic motifs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a fundamental building block for fluorinated liquid crystal compounds and organic light-emitting diode (OLED) materials, improving electronic properties and device performance.
• Polymer & Resin Modifier: Incorporated into high-performance polymers and epoxy resins to alter thermal stability, solubility, and chemical resistance.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a versatile scaffold for constructing complex heterocycles.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Item	Detail
Product Name	4'-Fluoro-Biphenyl-3-Ylamine
CAS No.	10540-45-1
Molecular Formula	C12H10FN
Molecular Weight	187.21 g/mol
Synonyms	3-Amino-4'-fluorobiphenyl; 4'-Fluoro[1,1'-biphenyl]-3-amine; 4-Fluorobiphenyl-3-amine; (3-Aminophenyl)(4-fluorophenyl)methane; Biphenyl-3-amine, 4'-fluoro-; 4'-Fluoro-3-biphenylamine
EINECS	Contact for details

Quality Control

Every batch of 4'-Fluoro-Biphenyl-3-Ylamine is manufactured under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.