Description

L-Leucinamide Hydrochloride is a high-purity, protected amino acid derivative essential for advanced organic synthesis and peptide research. Its primary value lies in serving as a key chiral building block for the controlled introduction of the leucine side chain, enabling the production of complex bioactive molecules. This compound is critically needed by pharmaceutical R&D teams, peptide synthesis specialists, and fine chemical manufacturers developing novel therapeutics and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected leucine residue to construct specific peptide sequences.
• Biochemical Research: Employed in the study of enzyme substrates, inhibitors, and metabolic pathways involving leucine.
• Fine Chemical Production: Acts as a chiral synthon for manufacturing complex organic molecules requiring high stereochemical purity.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	L-Leucinamide Hydrochloride
CAS No.	10466-61-2
Molecular Formula	C6H15ClN2O
Molecular Weight	166.65 g/mol
Synonyms	L-Leucine amide hydrochloride; (S)-2-Amino-4-methylpentanamide hydrochloride; H-Leu-NH2·HCl; Leucinamide hydrochloride; L-2-Amino-4-methylvaleramide hydrochloride; (S)-Leucinamide hydrochloride; Leucine amide monohydrochloride; L-α-Aminoisocaproamide hydrochloride
EINECS	233-954-6

Quality Control

Our L-Leucinamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥98% by HPLC), and specific parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	+14.0° to +16.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.