Description

Eledoisin C-Terminal Heptapeptide CAS NO 10465-12-0 is a bioactive synthetic peptide fragment corresponding to the C-terminal sequence of the neuropeptide eledoisin. This compound is a critical research tool for studying tachykinin receptor pharmacology and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in neuroscience, cardiovascular research, and drug discovery programs.

Application

• Pharmacological Research: Used as a reference standard and agonist in studies targeting tachykinin NK1, NK2, and NK3 receptors.
• Neuroscience Studies: Investigates the role of tachykinin peptides in pain transmission, neurogenic inflammation, and central nervous system functions.
• Drug Discovery & Development: Serves as a key intermediate or biological probe in the design and screening of novel neuropeptide analogues and receptor antagonists.
• Biochemical Assays: Employed in receptor binding assays, functional cell-based assays (e.g., calcium flux), and enzyme-linked immunosorbent assays (ELISAs) for system calibration.
• Academic & Institutional Research: Supports basic science research in physiology and peptide chemistry at universities and government laboratories.
• Peptide Synthesis & Custom Manufacturing: Acts as a building block or template for the synthesis of longer peptide sequences or modified analogues with enhanced properties.

Basic Information

Product Name	Eledoisin C-Terminal Heptapeptide
CAS No.	10465-12-0
Molecular Formula	C38H62N12O10S
Molecular Weight	854.0 g/mol
Synonyms	Eledoisin (6-13); Eledoisin C-Terminal Fragment; H-Phe-Gly-Leu-Met-NH2 (incorrect but common misnomer); [pGlu6, Pro9]-SP(6-11); Pyr-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 (Eledoisin full sequence for context); Tachykinin Peptide Fragment; Neurokinin Receptor Agonist Peptide
EINECS	Contact for details

Quality Control

Our Eledoisin C-Terminal Heptapeptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with each shipment, detailing results for assay, purity by HPLC, amino acid analysis, and mass spectrometry. Our quality standards align with GMP principles for research-grade bioactive peptides.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dimethyl sulfoxide (DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.