Description

S-(Carboxymethyl)Glutathione is a chemically modified derivative of the essential tripeptide glutathione, featuring a carboxymethyl group attached to the sulfur atom. This modification enhances its stability and alters its reactivity profile, making it a valuable biochemical tool and a potential precursor in advanced synthesis. It is primarily utilized in pharmaceutical research, biochemical studies, and as a reference standard in analytical chemistry. The compound is identified by the CAS number 10463-61-3.

Application

• Biochemical Research: Used as a stable, modified substrate to study glutathione metabolism, enzyme kinetics (e.g., glutathione S-transferases), and redox signaling pathways.
• Pharmaceutical Intermediates: Serves as a key building block or precursor in the synthesis of novel drug candidates targeting oxidative stress and detoxification pathways.
• Analytical Reference Standard: Employed as a high-purity calibrant in HPLC, LC-MS, and other chromatographic methods for the quantification of glutathione and its derivatives in complex matrices.
• Cosmeceutical Development: Investigated for its potential antioxidant properties in advanced skincare formulations aimed at mitigating cellular damage.
• Enzyme Inhibition Studies: Acts as a potential inhibitor or modulator for enzymes that interact with native glutathione, aiding in mechanistic studies.

Basic Information

Product Name	S-(Carboxymethyl)Glutathione
CAS No.	10463-61-3
Molecular Formula	C11H18N3O8S
Molecular Weight	352.34 g/mol
Synonyms	Glutathione, S-(carboxymethyl)-; NSC 113236; γ-Glutamyl-S-(carboxymethyl)cysteinylglycine; S-Carboxymethylglutathione; (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-(carboxymethylthio)ethyl]carbamoyl}butanoic acid
EINECS	233-947-8

Quality Control

Our S-(Carboxymethyl)Glutathione is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.