Description

Isopropyl-Diiodothyronine is a synthetic thyroid hormone analog, a derivative of thyronine. This compound is of significant interest in biochemical and pharmaceutical research for its potential to modulate metabolic pathways and thyroid hormone receptor activity. It serves as a critical intermediate and reference standard for researchers and manufacturers in the fields of endocrinology, drug discovery, and metabolic disease studies.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of novel thyroid hormone analogs and receptor modulators.
• Biochemical Studies: Acts as a reference standard and tool compound for investigating thyroid hormone signaling, metabolism, and receptor binding affinity.
• Endocrinology Research: Employed in metabolic studies to understand the effects of thyroid hormone derivatives on lipid and carbohydrate metabolism.
• Drug Discovery: Serves as a building block for creating potential therapeutic agents targeting thyroid hormone-related disorders.
• Analytical Chemistry: Used as a certified reference material (CRM) for method development and validation in analytical laboratories.

Basic Information

Product Name	Isopropyl-Diiodothyronine
CAS No.	10439-94-8
Molecular Formula	C15H13I2NO4
Molecular Weight	541.08 g/mol
Synonyms	3,5-Diiodo-O-(1-methylethyl)-L-thyronine; 3,5-Diiodo-O-isopropylthyronine; O-Isopropyl-3,5-diiodothyronine; Isopropyl DIIT; DIIT-O-iPr; (2S)-2-Amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]-2-methylpropanoic acid (IUPAC); Thyroid hormone analog O-isopropyl derivative
EINECS	Contact for details

Quality Control

Our Isopropyl-Diiodothyronine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.