Description

p-Toluenesulfinyl Chloride is a versatile organosulfur reagent primarily used as a key sulfenylating and sulfinylating agent in organic synthesis. Its high reactivity makes it an essential building block for constructing complex sulfur-containing molecules, including sulfoxides and sulfonamides. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and efficient synthetic pathways.

Application

• Pharmaceutical Intermediates: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for sulfoxide-based drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that contain sulfinyl or sulfonamide functional groups.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, and other specialty chemicals requiring sulfenyl chloride chemistry.
• Polymer Chemistry: Employed as a modifying agent or cross-linking initiator in the synthesis of specialty polymers and resins.
• Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel sulfur compounds.
• Peptide Modification: Used for the selective modification of cysteine residues in peptides and proteins.

Basic Information

Product Name	p-Toluenesulfinyl Chloride
CAS No.	10439-23-3
Molecular Formula	C7H7ClOS
Molecular Weight	174.64 g/mol
Synonyms	4-Methylbenzenesulfinyl chloride; p-Toluenesulfenic acid chloride; 4-Toluenesulfinyl chloride; Tosylsulfinyl chloride; (4-Methylphenyl)sulfinyl chloride; p-Tolylsulfinyl chloride; Benzenesulfinyl chloride, 4-methyl-
EINECS	233-941-5

Quality Control

Our p-Toluenesulfinyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure containers are kept tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.