Description

Selenocysteine CAS NO 10236-58-5 is the 21st proteinogenic amino acid, distinguished by the presence of selenium within a selenol (-SeH) group in place of the sulfur-containing thiol found in cysteine. This unique structure makes it a critical component of selenoproteins, which are essential for powerful antioxidant defense and redox regulation in biological systems. It is a vital raw material for researchers in biochemistry and pharmaceutical development, particularly for studying and synthesizing selenoenzymes like glutathione peroxidase and thioredoxin reductase.

Application

• Biochemical Research: Essential for the study of selenoprotein synthesis, function, and the role of selenium in human health and disease models.
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic agents targeting oxidative stress, such as in cancer and neurodegenerative disorders.
• Nutraceutical & Dietary Supplement Formulation: A key ingredient in advanced supplement research aimed at boosting antioxidant capacity and supporting thyroid hormone metabolism.
• Enzyme Engineering: Employed in the production and study of engineered selenoenzymes with enhanced catalytic activity for industrial biocatalysis.
• Cell Culture Media Supplement: Used in specialized mammalian cell culture to ensure proper selenoprotein expression under controlled research conditions.
• Reference Standard: Serves as a high-purity analytical standard in HPLC, MS, and NMR for quality control in related pharmaceutical and nutritional products.

Basic Information

Item	Details
Product Name	Selenocysteine
CAS No.	10236-58-5
Molecular Formula	C3H7NO2Se
Molecular Weight	168.05 g/mol
Synonyms	L-Selenocysteine; (R)-2-Amino-3-selenopropanoic acid; 3-Selenyl-L-alanine; Sec; U; Selenium analog of cysteine; Selenocystein; Selenocystine (note: this is the dimeric, oxidized form)
EINECS	233-585-9

Quality Control

Our Selenocysteine is produced and tested under strict quality management protocols. We offer material suitable for research and development purposes, with typical purity levels exceeding 95% (HPLC). Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While not intended for direct human use as supplied, our quality systems ensure consistency, traceability, and reliability for your critical R&D and manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), long-term storage is recommended at -20°C under an inert gas such as argon or nitrogen. For short-term use, store desiccated at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Optical Rotation	[α]20/D: Specific range provided on COA
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.