Description

N(Alpha)-Acetylglycyllysyl Methyl Ester is a protected dipeptide derivative, specifically an acetylated glycyl-lysine methyl ester. This compound serves as a crucial building block (synthon) in advanced peptide synthesis, offering controlled reactivity for constructing complex molecular architectures. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Peptide Library Construction: Essential building block for combinatorial chemistry and high-throughput screening of bioactive peptides.
• Proteomics & Diagnostics: Can be incorporated into labeled peptides used as internal standards in mass spectrometry or diagnostic assays.
• Cosmetic Peptide Synthesis: Potential intermediate for the production of certain bioactive peptides used in skincare formulations.
• Academic & Institutional R&D: Serves as a standard or starting material in university and government laboratory research projects.

Basic Information

Product Name	N(Alpha)-Acetylglycyllysyl Methyl Ester
CAS No.	10236-44-9
Molecular Formula	C11H21N3O4
Molecular Weight	259.30 g/mol
Synonyms	Ac-Gly-Lys-OMe; Nα-Acetyl-Gly-Lys-OMe; N-Acetylglycyl-L-lysine Methyl Ester; Acetyl-glycyl-lysine methyl ester; L-Lysine, N2-acetyl-N6-(methoxycarbonylmethyl)-; Nα-Acetyl-Nε-(methoxycarbonylmethyl)-L-lysine; N(Alpha)-Acetylglycyl-L-lysine Methyl Ester; Ac-Gly-Lys(OCH3)-OH (deprotected form reference)
EINECS	Contact for details

Quality Control

Our N(Alpha)-Acetylglycyllysyl Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.