Description

(2R)-2,3,3Aβ,9Aβ-Tetrahydro-3β-Hydroxy-2α-(Hydroxymethyl)-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidine-6-Thione is a complex heterocyclic organic compound featuring fused furan, oxazole, and pyrimidine rings, which is of significant interest in advanced pharmaceutical research and development. Its intricate molecular architecture makes it a valuable key intermediate or building block for synthesizing novel active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily sought by research institutions, pharmaceutical companies, and specialty chemical manufacturers engaged in the discovery of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting the central nervous system or possessing antiviral properties.
• Organic Synthesis Building Block: Used in research laboratories for constructing complex nitrogen- and oxygen-containing heterocycles, which are common motifs in medicinal chemistry.
• Biochemical Research: Employed as a reference standard or a tool compound in enzymatic studies and receptor binding assays due to its unique fused ring system.
• Fine Chemical Production: Acts as a starting material for the manufacture of specialty chemicals used in agrochemicals or advanced material science.
• Process Development & Scale-Up: Utilized by process chemists to develop and optimize scalable synthetic routes for pilot and commercial manufacturing.

Basic Information

Product Name	(2R)-2,3,3Aβ,9Aβ-Tetrahydro-3β-Hydroxy-2α-(Hydroxymethyl)-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidine-6-Thione
CAS No.	10190-42-8
Molecular Formula	C10H10N2O4S
Molecular Weight	254.26 g/mol
Synonyms	6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-6-thione, 2,3,3aβ,9aβ-tetrahydro-3β-hydroxy-2α-(hydroxymethyl)-, (2R)-; (2R)-2,3,3aβ,9aβ-Tetrahydro-3β-hydroxy-2α-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-6-thione; Furo[2',3':4,5]oxazolo[3,2-a]pyrimidine-6-thione derivative; (R)-enantiomer of the fused tricyclic thione; Oxazolo-furo-pyrimidine thione intermediate
EINECS	Contact for details

Quality Control

Our production of (2R)-2,3,3Aβ,9Aβ-Tetrahydro-3β-Hydroxy-2α-(Hydroxymethyl)-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidine-6-Thione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, chiral analysis, and NMR spectroscopy to confirm identity, purity, and enantiomeric excess. Comprehensive Certificates of Analysis (COA) detailing all specification results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; therefore, the container should be kept tightly sealed in a dry environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.