Description

Ethyl 2-Bromo-2,3,3,3-Tetrafluoropropionate is a versatile fluorinated building block and reagent of significant importance in advanced organic synthesis. Its value lies in the introduction of both bromine and multiple fluorine atoms, enabling precise molecular modifications that are difficult to achieve with other compounds. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials industries who require high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the introduction of the -CF3 group and other fluorinated motifs into potential drug candidates, particularly in medicinal chemistry for protease inhibitors and kinase modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination enhances biological activity, stability, and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Fluorinated Polymer Modification: Acts as a grafting agent or comonomer to incorporate bromine and fluorine functionalities into polymer backbones, altering surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in nucleophilic substitution and coupling reactions (e.g., Suzuki, Heck) to construct complex, fluorinated molecular architectures in R&D settings.
• Refrigerant & Propellant Research: Investigated as a potential intermediate or additive in the development of next-generation fluorocarbon-based working fluids.

Basic Information

Product Name	Ethyl 2-Bromo-2,3,3,3-Tetrafluoropropionate
CAS No.	10186-73-9
Molecular Formula	C5H5BrF4O2
Molecular Weight	237.00 g/mol
Synonyms	2-Bromo-2,3,3,3-tetrafluoropropionic Acid Ethyl Ester; Ethyl α-Bromo-α,β,β,β-tetrafluoropropionate; Ethyl 2-Bromotetrafluoropropionate; 2-Bromo-2,3,3,3-tetrafluoropropanoic Acid Ethyl Ester; Propanoic acid, 2-bromo-2,3,3,3-tetrafluoro-, ethyl ester; NSC 163045; Tetrafluoroethyl bromopropionate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-2,3,3,3-Tetrafluoropropionate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 8°C for long-term stability, although the product is typically stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to minimize moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.6 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.