Description

8-(Trifluoromethyl)-9H-Purin-2-Amine is a high-purity, fluorinated purine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical agents and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, nucleotide chemistry, and the creation of specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential antiviral, anticancer, and anti-inflammatory drug candidates.
• Agrochemical Research: Used in developing new herbicides, pesticides, and plant growth regulators that leverage the biological activity of purine scaffolds.
• Nucleotide Analog Synthesis: Serves as a modified base for creating fluorinated nucleoside and nucleotide analogs for biochemical and therapeutic applications.
• Chemical Biology Probes: Employed in the design of enzyme inhibitors and molecular probes to study purine-binding proteins and biological pathways.
• Material Science: Potential monomer or additive for creating specialized polymers and electronic materials.

Basic Information

Product Name	8-(Trifluoromethyl)-9H-Purin-2-Amine
CAS No.	10179-89-2
Molecular Formula	C6H4F3N5
Molecular Weight	203.12 g/mol
Synonyms	2-Amino-8-(trifluoromethyl)purine; 8-(Trifluoromethyl)guanine; 8-Trifluoromethylguanine; 2-Amino-8-trifluoromethyl-9H-purine; 9H-Purin-2-amine, 8-(trifluoromethyl)-; 8-CF3-Guanine; 8-Trifluoromethyl-2-aminopurine
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)-9H-Purin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.