Description

(2S,3R)-2-Amino-3-Hydroxy-Hexanoic Acid CAS NO 10148-69-3 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at the 2 and 3 carbon positions. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceuticals and bioactive molecules. It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical sectors, where precise stereochemical control is paramount for drug efficacy and safety.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of protease inhibitors, antibiotics, and other active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate specific stereocenters into peptide chains for research and therapeutic peptides.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway analysis, and as a substrate analog.
• Asymmetric Synthesis Catalyst: Can be utilized as a precursor or ligand in the development of chiral catalysts for asymmetric transformations.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	(2S,3R)-2-Amino-3-Hydroxy-Hexanoic Acid
CAS No.	10148-69-3
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2S,3R)-2-Amino-3-hydroxycaproic acid; (2S,3R)-3-Hydroxy-L-norleucine; L-threo-3-Hydroxynorleucine; (2S,3R)-3-Hydroxy-2-aminocaproic acid; 2-Amino-3-hydroxyhexanoic acid (specified isomer); β-Hydroxynorleucine; Norleucine, 3-hydroxy-, L-threo-
EINECS	Contact for details

Quality Control

Our (2S,3R)-2-Amino-3-Hydroxy-Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets stringent specifications for research and GMP-grade applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.