Description

4-Amino-2,6-Dichloropyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino group and reactive chlorine atoms, makes it an indispensable intermediate for constructing complex heterocyclic systems. This high-purity compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for developing herbicides, fungicides, and plant growth regulators.
• Material Science Research: Used in the creation of organic electronic materials, ligands for metal complexes, and specialty polymers.
• Dye and Pigment Manufacturing: Intermediate for producing heterocyclic dyes and colorants.
• Biochemical Research: Serves as a scaffold for designing enzyme inhibitors and molecular probes.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name	4-Amino-2,6-Dichloropyrimidine
CAS No.	10132-07-7
Molecular Formula	C4H3Cl2N3
Molecular Weight	163.99 g/mol
Synonyms	2,6-Dichloro-4-pyrimidinamine; 4-Pyrimidinamine, 2,6-dichloro-; 2,6-Dichloropyrimidin-4-amine; NSC 403697; 4-Amino-2,6-dichloropyrimidine; 2,6-Dichloro-4-aminopyrimidine
EINECS	233-366-5

Quality Control

Our 4-Amino-2,6-Dichloropyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The compound may be hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.