Description

Cyclo(-Gly-Phe) CAS NO 10125-07-2 is a cyclic dipeptide, also known as a diketopiperazine (DKP), composed of glycine and L-phenylalanine. This compound serves as a crucial pharmacophore and building block in medicinal chemistry and peptide research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and manufacturers of advanced intermediates for drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the development of novel therapeutic agents, including protease inhibitors and receptor modulators.
• Peptide Mimetics Research: Used to study constrained peptide structures and their biological activities, providing insights into drug design.
• Biochemical Tool Compound: Employed in enzymatic studies and as a reference standard in analytical method development for peptide analysis.
• Cosmetic Peptide Synthesis: Acts as a precursor for synthesizing bioactive peptides used in advanced skincare formulations.
• Academic & Industrial R&D: A key material for investigating diketopiperazine chemistry and its applications in material science and bioorganic chemistry.

Basic Information

Product Name	Cyclo(-Gly-Phe)
CAS No.	10125-07-2
Molecular Formula	C11H12N2O2
Molecular Weight	204.23 g/mol
Synonyms	Cyclo(glycyl-L-phenylalanyl); Cyclo(Gly-Phe); 3-Benzyl-2,5-piperazinedione; Glycine-Phenylalanine Diketopiperazine; L-Phenylalanylglycine Anhydride; 2,5-Diketopiperazine, 3-benzyl-; Diketopiperazine (Gly-Phe); DKPs (Gly-Phe)
EINECS	233-345-3

Quality Control

Our Cyclo(-Gly-Phe) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.