Description

1,2,4-Triazolyl-3-Alanine is a non-proteinogenic amino acid derivative featuring a 1,2,4-triazole heterocycle. This unique structure makes it a valuable synthetic intermediate and building block for advanced chemical synthesis. It is primarily utilized in pharmaceutical research and development, particularly in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel drug candidates, especially those targeting enzymes or receptors where the triazole moiety can enhance binding affinity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its heterocyclic structure for biological activity.
• Peptidomimetics: Incorporated into peptide analogs to modify stability, bioavailability, and pharmacological properties.
• Biochemical Research: Serves as a specialized reagent in studying amino acid metabolism and enzyme inhibition.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Synthesis: A versatile intermediate for creating complex heterocyclic compounds in custom synthesis projects.

Basic Information

Product Name	1,2,4-Triazolyl-3-Alanine
CAS No.	10109-05-4
Molecular Formula	C5H8N4O2
Molecular Weight	156.14 g/mol
Synonyms	3-(1H-1,2,4-Triazol-1-yl)-L-alanine; (S)-2-Amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid; L-1,2,4-Triazolylalanine; 1,2,4-Triazole-1-alanine; 3-(1,2,4-Triazolyl)-L-alanine; 10109-05-4; 1,2,4-Triazol-1-yl-L-alanine
EINECS	Contact for details

Quality Control

Our 1,2,4-Triazolyl-3-Alanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific batch results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.