Description

n-Acetyl-Dl-Histidine, Hydrate is a chemically modified derivative of the amino acid histidine, widely utilized in biochemical and pharmaceutical research. This compound is valued for its role as a precursor and building block in peptide synthesis and metabolic studies. It serves as a critical raw material for researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries.

Application

• Pharmaceutical Intermediates: Used as a key chiral building block in the synthesis of more complex active pharmaceutical ingredients (APIs) and peptides.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway analysis, and as a substrate or inhibitor in various biochemical assays.
• Cosmetic & Skincare Formulations: Incorporated into advanced cosmetic products for its potential moisturizing and skin-conditioning properties.
• Nutritional Science: Investigated for its role in amino acid metabolism and as a component in specialized nutritional supplements.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in laboratories.

Basic Information

Product Name	n-Acetyl-Dl-Histidine, Hydrate
CAS No.	10101-30-1
Molecular Formula	C8H11N3O3 • xH2O
Molecular Weight	197.19 g/mol (Anhydrous basis)
Synonyms	N-Acetyl-DL-histidine hydrate; Nα-Acetyl-DL-histidine hydrate; DL-α-Acetamido-4(5)-imidazolepropionic acid hydrate; Acetylhistidine; (±)-N-Acetylhistidine; NSC 401565; 2-Acetamido-3-(1H-imidazol-4-yl)propanoic acid hydrate
EINECS	233-300-6

Quality Control

Our n-Acetyl-Dl-Histidine, Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the product should be kept under conditions of low humidity. For long-term storage, a temperature of 2-8°C is recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 12.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.