Description

5-Trifluoromethyl-1H-Benzoimidazol-2-Ylamine is a high-value, multi-functional heterocyclic building block characterized by its benzoimidazole core and trifluoromethyl substituent. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure imparts critical electronic and steric properties. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Dye and Pigment Intermediate: Acts as a precursor for specialized heterocyclic dyes and pigments with specific light-absorption properties.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for custom synthesis projects and scale-up services.

Basic Information

Product Name	5-Trifluoromethyl-1H-Benzoimidazol-2-Ylamine
CAS No.	10057-46-2
Molecular Formula	C8H6F3N3
Molecular Weight	201.15 g/mol
Synonyms	2-Amino-5-(trifluoromethyl)-1H-benzimidazole; 5-(Trifluoromethyl)-1H-benzimidazol-2-amine; 2-Amino-5-trifluoromethylbenzimidazole; 1H-Benzimidazol-2-amine, 5-(trifluoromethyl)-; 5-Trifluoromethyl-2-benzimidazolamine; Benzimidazole, 2-amino-5-(trifluoromethyl)-; 5-Trifluoromethyl-2-aminobenzimidazole
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available upon request for every batch, detailing identity, purity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.