Description

2',4'-Difluoro-n-Methylacetanilide is a specialized fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce difluoromethyl or related fluorinated motifs into their target structures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and pesticides where the introduction of fluorine atoms enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials for next-generation electronics.
• Fluorinated Dye & Pigment Intermediate: Used to synthesize specialty dyes and pigments with improved lightfastness and chemical resistance for high-performance coatings and inks.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2',4'-Difluoro-n-Methylacetanilide
CAS No.	10016-06-5
Molecular Formula	C9H9F2NO
Molecular Weight	185.17 g/mol
Synonyms	N-(2,4-Difluorophenyl)-N-methylacetamide; 2',4'-Difluoro-N-methylacetanilide; N-Methyl-2,4-difluoroacetanilide; Acetamide, N-(2,4-difluorophenyl)-N-methyl-; 1-(2,4-Difluorophenyl)-N-methylethanamine; N-Methyl-N-(2,4-difluorophenyl)acetamide
EINECS	Contact for details

Quality Control

Our 2',4'-Difluoro-n-Methylacetanilide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.