Description

2-(2-Amino-4-Methyl-Phenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol is a specialized fluorinated organic compound featuring a unique combination of an aromatic amine and a hexafluoro-isopropanol group. This structure makes it a valuable and versatile building block (synthon) for advanced chemical synthesis, particularly in the development of novel materials and active pharmaceutical ingredients. It is primarily sought after by research and development (R&D) teams and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those requiring fluorinated motifs for enhanced metabolic stability, bioavailability, or receptor binding.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and biological activity.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated into specialty polymers to impart unique properties such as chemical resistance, thermal stability, or altered surface characteristics.
• Complex Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands for catalysis and material science applications.
• Dye & Pigment Intermediate: Acts as a precursor for the synthesis of specialized fluorinated dyes and functional pigments.

Basic Information

Product Name	2-(2-Amino-4-Methyl-Phenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol
CAS No.	1992-08-1
Molecular Formula	C10H9F6NO
Molecular Weight	273.18 g/mol
Synonyms	2-(2-Amino-4-methylphenyl)-1,1,1,3,3,3-hexafluoro-2-propanol; 2-Amino-α,α-bis(trifluoromethyl)-4-methylbenzenemethanol; 1,1,1,3,3,3-Hexafluoro-2-(2-amino-4-methylphenyl)propan-2-ol; 2-Amino-4-methyl-α,α-bis(trifluoromethyl)benzyl alcohol; Hexafluoroacetone 2-amino-p-toluidine adduct; HFA-2-amino-p-toluidine adduct
EINECS	Contact for details

Quality Control

Our production of 2-(2-Amino-4-Methyl-Phenyl)-1,1,1,3,3,3-Hexafluoro-Propan-2-Ol adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can compromise product integrity. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.