Description

5-Fluoro-2-Methoxyaniline is a versatile fluorinated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an electron-donating methoxy group and a fluorine atom, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides that require fluorinated aniline moieties for enhanced bioactivity and stability.
• Liquid Crystal & OLED Materials: Used in the production of fluorinated aromatic amines for electronic display technologies and organic light-emitting diodes (OLEDs).
• Dye & Pigment Manufacturing: Intermediate for synthesizing specialized azo dyes and pigments where fluorine substitution improves lightfastness and color properties.
• Polymer Chemistry: Monomer or modifier in the creation of high-performance polymers, such as polyimides and epoxy resins, for electronics and aerospace applications.
• Chemical Research & Development: A valuable reagent for medicinal chemistry, process development, and exploring new synthetic methodologies in academic and industrial labs.

Basic Information

Product Name	5-Fluoro-2-Methoxyaniline
CAS No.	1978-39-8
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	2-Amino-4-fluoroanisole; 4-Fluoro-2-aminoanisole; 5-Fluoro-o-anisidine; 2-Methoxy-5-fluoroaniline; 5-Fluoro-2-methoxybenzenamine; 5-Fluoro-2-methoxyphenylamine; 2-Methoxy-5-fluorobenzenamine
EINECS	217-849-9

Quality Control

Our 5-Fluoro-2-Methoxyaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged procedures to minimize oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.