Description

Dehydroalanine is a versatile, non-proteinogenic amino acid derivative characterized by its unique α,β-unsaturated structure, making it a valuable building block in organic synthesis and biochemical research. This compound is essential for creating advanced peptide mimetics and studying enzyme inhibition mechanisms due to its reactive dehydro moiety. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, proteomics, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and peptide-based therapeutics.
• Biochemical Research: Used as a mechanism-based inhibitor to study the activity of pyridoxal phosphate-dependent enzymes, such as cystathionine β-synthase.
• Peptide Chemistry: Incorporated into peptides to introduce conformational constraints or as a site for selective chemical modification.
• Proteomics & Labeling: Serves as a reactive handle in bioconjugation strategies for labeling proteins and antibodies.
• Food Science Research: Investigated for its role as a potential cross-linking agent or as a marker in food protein analysis.
• Material Science: Explored for the development of novel polymers and functional materials with tailored properties.

Basic Information

Product Name	Dehydroalanine
CAS No.	1948-56-7
Molecular Formula	C3H5NO2
Molecular Weight	87.08 g/mol
Synonyms	2-Aminoprop-2-enoic acid; (Z)-2-Aminoprop-2-enoic acid; 2,3-Didehydroalanine; DHA; Dehydroalanine free base; α,β-Dehydroalanine; 2-Aminoacrylic acid; 2-Propenoic acid, 2-amino-
EINECS	217-764-7

Quality Control

Our Dehydroalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.