Description

2-Chloro-5-Nitropyrimidin-4-Amine is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both chloro and nitro substituents on the pyrimidine ring, makes it a critical intermediate for constructing complex molecules with targeted biological activity. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for exploring new chemical entities and reaction pathways in academic and industrial labs.
• Material Science: Potential building block for creating specialty polymers, dyes, and functional materials with specific electronic properties.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	2-Chloro-5-Nitropyrimidin-4-Amine
CAS No.	1920-66-7
Molecular Formula	C4H3ClN4O2
Molecular Weight	174.55 g/mol
Synonyms	4-Amino-2-chloro-5-nitropyrimidine; 2-Chloro-5-nitro-4-pyrimidinamine; 5-Nitro-2-chloropyrimidin-4-amine; 2-Chloro-5-nitropyrimidin-4-ylamine; 4-Pyrimidinamine, 2-chloro-5-nitro-; 1920-66-7; 2-Chloro-5-nitro-4-aminopyrimidine
EINECS	217-671-8

Quality Control

Our 2-Chloro-5-Nitropyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications are provided for each lot, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.